The Indianapolis Colts (2-4) have become slightly bigger underdogs as the week has progressed in the Week 7 matchup with the San Francisco 49ers (2-3) at Levi’s Stadium.
The prime-time bout opened with a typical 3.5-point spread favoring the 49ers. As of Friday morning, the spread shifted even more in the favor of the 49ers, per Tipico Sportsbook.
Here are the updated odds for the Week 7 matchup between the Colts and 49ers:
| Spread | Moneyline | Total Points | |
| Indianapolis Colts (2-4) | +4.5 | +170 | O 43.5 -115 |
| San Francisco 49ers (2-3) | -4.5 | -210 | U 43.5 -105 |
The changes come to the spread and the moneyline. The 49ers are now favored by 4.5 points while the moneyline also shifted by 10 in favor of the home team. The over/under remains the same as the opening odds from earlier in the week.
This shift in the odds could come due to the fact that the Colts lost play-making safety Julian Blackmon to a torn Achilles he suffered on the last play of practice Wednesday.
That, along with several other injuries, could be factors in the 49ers becoming bigger favorites in Week 7.
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