The Week 5 college football predictions, TV schedules, and game times, broken down by conference.
All Listed Gametimes EST
Week 5 Fearless Predictions, Game Previews
ACC | Big Ten | Big 12 | Pac-12 | SEC
– CFN Fearless Predictions & Game Previews
– Week 5 Expert Picks & Predictions
– Week 5 10 Best Picks Against The Spread
– Week 5 10 Best Point Total Picks
– Week 5 Final Thoughts & Betting Advice
Week 5 Schedule, Predictions
– C-USA, IND, MAC. M-West
– Pac-12, SEC, Sun Belt
ACC Schedule
– ACC Team-by-Team Schedules & Predictions
Results So Far: SU 35-10, ATS 19-16-1, o/u: 18-18
Click on each game for game preview & prediction
Friday, September 27th
Duke at Virginia Tech
Prediction: Duke 30, Virginia Tech 27
BetMGM Line: Virginia Tech -3, o/u: 52.5
Final Score: Duke 45, Virginia Tech 10
Saturday, September 28th
Holy Cross at Syracuse
Prediction: Syracuse 48, Holy Cross 10
BetMGM Line: No Line, o/u: No Line
Final Score: COMING
Delaware at Pitt
Prediction: Pitt 41, Delaware 17
BetMGM Line: No Line, o/u: No Line
Final Score: Pitt 17, Delaware 14
Clemson at North Carolina
Prediction: Clemson 40, North Carolina 16
BetMGM Line: Clemson -27.5, o/u: 60.5
Final Score: Clemson 21, North Carolina 20
Virginia at Notre Dame
Prediction: Virginia 24, Notre Dame 23
BetMGM Line: Notre Dame -10.5, o/u: 46.5
Final Score: Notre Dame 35, Virginia 20
Georgia Tech at Temple
Prediction: Temple 26, Georgia Tech 20
BetMGM Line: Temple -9, o/u: 49
Final Score: Temple 24, Georgia Tech 2
Wake Forest at Boston College
Prediction: Wake Forest 34, Boston College 27
BetMGM Line: Wake Forest -5, o/u: 69.5
Final Score: Wake Forest 27, Boston College 24
NC State at Florida State
Prediction: Florida State 34, NC State 30
BetMGM Line: Florida State -7, o/u: 62.5
Final Score: Florida State 31, NC State 13
American Athletic Schedule
– AAC Team-by-Team Schedules & Predictions
Results So Far: SU 32-7, ATS 14-15, o/u: 16-11
Click on each game for game preview & prediction
Thursday, September 26th
Navy at Memphis
Prediction: Memphis 34, Navy 27
BetMGM Line: Memphis -11.5, o/u: 54.5
Final Score: Memphis 35, Navy 23
Saturday, September 28th
Georgia Tech at Temple
Prediction: Temple 26, Georgia Tech 20
BetMGM Line: Temple -9, o/u: 49
Final Score: Temple 24, Georgia Tech 2
SMU at USF
Prediction: SMU 34, USF 26
BetMGM Line: SMU -7.5, o/u: 62.5
Final Score: SMU 48, USF 21
Cincinnati at Marshall
Prediction: Cincinnati 21, Marshall 17
BetMGM Line: Cincinnati -3.5, o/u: 47.5
Final Score: Cincinnati 52, Marshall 14
East Carolina at Old Dominion
Prediction: Old Dominion 24, East Carolina 20
BetMGM Line: Old Dominion -2.5, o/u: 48.5
Final Score: East Carolina 24, Old Dominion 21
UConn at UCF
Prediction: UCF 55, UConn 14
BetMGM Line: UCF -42.5, o/u: 64.5
Prediction: UCF 56, UConn 21
Houston at North Texas
Prediction: North Texas 34, Houston 3
BetMGM Line: North Texas -7.5, o/u: 59
Final Score: Houston 46, North Texas 25
Big Ten Schedule
– Big Ten Team-by-Team Schedules & Predictions
Results So Far: SU 38-4, ATS 18-19-1, o/u: 22-14-1
Click on each game for game preview & prediction
Friday, September 27th
Penn State at Maryland
Prediction: Maryland 27, Penn State 23
BetMGM Line: Penn State -6.5, o/u: 59.5
Final Score: Penn State 59, Maryland 0
Saturday, September 28th
Rutgers at Michigan
12:00 Big Ten Network | Get Tickets
Prediction: Michigan 34, Rutgers 10
BetMGM Line: Michigan -27.5, o/u: 48
Final Score: Michigan 52, Rutgers 0
Indiana at Michigan State
Prediction: Michigan State 30, Indiana 13
BetMGM Line: Michigan State -14, o/u: 45.5
Final Score: Michigan State 40, Indiana 31
Northwestern at Wisconsin
Prediction: Wisconsin 34, Northwestern 10
BetMGM Line: Wisconsin -24.5, o/u: 45.5
Final Score: Wisconsin 24, Northwestern 15
Middle Tennessee at Iowa
Prediction: Iowa 38, Middle Tennessee 13
BetMGM Line: Iowa -23.5, o/u: 52.5
Final Score: Iowa 48, Middle Tennessee 3
Minnesota at Purdue
Prediction: Minnesota 34, Purdue 30
BetMGM Line: Minnesota -2, o/u: 55.5
Final Score: Minnesota 38, Purdue 31
Ohio State at Nebraska
Prediction: Ohio State 45, Nebraska 23
BetMGM Line: Ohio State -17.5, o/u: 67.5
Final Score: Ohio State 48, Nebraska 7
Big 12 Schedule
– Big 12 Team-by-Team Schedules & Predictions
Results So Far: SU 27-7, ATS 10-13, o/u: 13-11
Click on each game for game preview & prediction
Texas Tech at Oklahoma
BetMGM Line: Oklahoma 45, Texas Tech 24
BetMGM Line: Oklahoma -27, o/u: 68.5
Final Score: Oklahoma 55, Texas Tech 16
Kansas at TCU
Prediction: TCU 38, Kansas 23
BetMGM Line: TCU -14.5, o/u: 49.5
Final Score: TCU 51, Kansas 14
Iowa State at Baylor
Prediction: Iowa State 26, Baylor 21
BetMGM Line: Iowa State -2.5, o/u: 55.5
Final Score: Baylor 23, Iowa State 21
Kansas State at Oklahoma State
Prediction: Oklahoma State 35, Kansas State 31
BetMGM Line: Oklahoma State -4, o/u: 60
Final Score: Oklahoma State 26, Kansas State 13
Week 5 Schedule, Predictions
– C-USA, IND, MAC. M-West
– Pac-12, SEC, Sun Belt
NEXT: Conference USA, Independents, MAC, Mountain West, Pac-12, SEC, Sun Belt
Week 5 Fearless Predictions, Game Previews
ACC | Big Ten | Big 12 | Pac-12 | SEC
– CFN Fearless Predictions & Game Previews
– Week 5 Expert Picks & Predictions
– Week 5 10 Best Picks Against The Spread
– Week 5 10 Best Point Total Picks
– Week 5 Final Thoughts & Betting Advice
Conference USA Schedule
– C-USA Team-by-Team Schedules & Predictions
Results So Far: SU 42-5, ATS 16-18, o/u: 20-14
Click on each game for game preview & prediction
Middle Tennessee at Iowa
Prediction: Iowa 38, Middle Tennessee 13
BetMGM Line: Iowa -23.5, o/u: 52.5
Final Score: Iowa 48, Middle Tennessee 3
Florida Atlantic at Charlotte
Prediction: Florida Atlantic 38, Charlotte 34
BetMGM Line: Charlotte -1.5, o/u: 64.5
Final Score: Florida Atlantic 45, Charlotte 27
Cincinnati at Marshall
Prediction: Cincinnati 21, Marshall 17
BetMGM Line: Cincinnati -3.5, o/u: 47.5
Final Score: Cincinnati 52, Marshall 14
East Carolina at Old Dominion
Prediction: Old Dominion 24, East Carolina 20
BetMGM Line: Old Dominion -2.5, o/u: 48.5
Final Score: East Carolina 24, Old Dominion 21
UTEP at Southern Miss
Prediction: Southern Miss 40, UTEP 17
BetMGM Line: Southern Miss -24.5, o/u: 49.5
Final Score: Southern Miss 31, UTEP 13
UAB at WKU
Prediction: UAB 27, WKU 20
BetMGM Line: UAB -2.5, o/u: 45.5
Final Score: WKU 20, UAB 13
Louisiana Tech at Rice
Prediction: Louisiana Tech 27, Rice 13
BetMGM Line: Louisiana Tech -8.5, o/u: 48.5
Final Score: Louisiana Tech 23, Rice 20 OT
Houston at North Texas
Prediction: North Texas 34, Houston 3
BetMGM Line: North Texas -7.5, o/u: 59
Final Score: Houston 46, North Texas 25
Independents Schedule
– Ind Team-by-Team Schedules & Predictions
Results So Far: SU 20-3, ATS 13-7, o/u: 12-8
Click on each game for game preview & prediction
BYU at Toledo
Prediction: BYU 34, Toledo 31
BetMGM Line: BYU -2, o/u: 59.5
Final Score: Toledo 28, BYU 21
Virginia at Notre Dame
Prediction: Virginia 24, Notre Dame 23
BetMGM Line: Notre Dame -10.5, o/u: 46.5
Final Score: Notre Dame 35, Virginia 20
Akron at UMass
Prediction: Akron 38, UMass 28
BetMGM Line: Akron -6.5, o/u: 63.5
Final Score: UMass 37, Akron 29
New Mexico at Liberty
Prediction: Liberty 48, New Mexico 42
BetMGM Line: Liberty -7.5, o/u: 71.5
Final Score: Liberty 17, New Mexico 10
Fresno State at New Mexico State
Prediction: Fresno State 44, New Mexico State 17
BetMGM Line: Fresno State -20.5, o/u: 60.5
Final Score: Fresno State 30, New Mexico State 17
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MAC Schedule
– MAC Team-by-Team Schedules & Predictions
Results So Far: SU 36-7, ATS 13-20, o/u: 19-10
Click on each game for game preview & prediction
Central Michigan at Western Michigan
Prediction: Western Michigan 37, Central Michigan 23
BetMGM Line: Western Michigan -17.5, o/u: 60.5
Final Score: Western Michigan 31, Central Michigan 15
Northern Illinois at Vanderbilt
Prediction: Vanderbilt 34, Northern Illinois 24
BetMGM Line: Vanderbilt -7, o/u: 54.5
Final Score: Vanderbilt 24, Northern Illinois 18
BYU at Toledo
Prediction: BYU 34, Toledo 31
BetMGM Line: BYU -2, o/u: 59.5
Final Score: Toledo 28, BYU 21
Buffalo at Miami University
Prediction: Buffalo 26, Miami University 20
BetMGM Line: Buffalo -2.5, o/u: 47.5
Final Score: Miami University 34, Buffalo 20
Akron at UMass
Prediction: Akron 38, UMass 28
BetMGM Line: Akron -6.5, o/u: 63.5
Final Score: UMass 37, Akron 29
Mountain West Schedule
– MW Team-by-Team Schedules & Predictions
Results So Far: SU 31-9, ATS 13-13-1, o/u: 14-13
Click on each game for game preview & prediction
Friday, September 27th
San Jose State at Air Force
Prediction: Air Force 35, San Jose State 17
BetMGM Line: Air Force -19.5, o/u: 56.5
Final Score: Air Force 41, San Jose State 24
Saturday, September 28th
New Mexico at Liberty
Prediction: Liberty 48, New Mexico 42
BetMGM Line: Liberty -7.5, o/u: 71.5
Final Score: Liberty 17, New Mexico 10
Colorado State at Utah State
Prediction: Utah State 48, Colorado State 30
BetMGM Line: Utah State -24, o/u: 70.5
Final Score: Utah State 34, Colorado State 24
UNLV at Wyoming
Prediction: Wyoming 23, UNLV 17
BetMGM Line: Wyoming -9, o/u: 47.5
Final Score: Wyoming 53, UNLV 17
Fresno State at New Mexico State
Prediction: Fresno State 44, New Mexico State 17
BetMGM Line: Fresno State -20.5, o/u: 60.5
Final Score: Fresno State 30, New Mexico State 17
Hawaii at Nevada
Prediction: Hawaii 34, Nevada 30
BetMGM Line: Nevada -2.5, o/u: 62.5
Final Score: Hawaii 54, Nevada 3
Week 5 Schedule, Predictions
– ACC, AAC, Big 12, Big Ten
– Pac-12, SEC, Sun Belt
NEXT: Pac-12, SEC, Sun Belt
Week 5 Fearless Predictions, Game Previews
ACC | Big Ten | Big 12 | Pac-12 | SEC
– CFN Fearless Predictions & Game Previews
– Week 5 Expert Picks & Predictions
– Week 5 10 Best Picks Against The Spread
– Week 5 10 Best Point Total Picks
– Week 5 Final Thoughts & Betting Advice
Pac-12 Schedule
– Pac-12 Team-by-Team Schedules & Predictions
Results So Far: SU 29-10, ATS 15-16, o/u: 22-7
Click on each game for game preview & prediction
Friday, September 27th
Arizona State at Cal
Prediction: Arizona State 23, Cal 20
BetMGM Line: Cal -4.5, o/u: 40.5
Final Score: Arizona State 24, Cal 17
Saturday, September 28th
Stanford at Oregon State
Prediction: Oregon State 30, Stanford 27
BetMGM Line: Stanford -3.5, o/u: 55.5
Final Score: Stanford 31, Oregon State 28
USC at Washington
Prediction: Washington 34, USC 20
BetMGM Line: Washington -9.5, o/u: 59.5
Final Score: Washington 28, USC 14
Washington State at Utah
Prediction: Utah 34, Washington State 27
BetMGM Line: Utah -4.5, o/u: 56.5
Final Score: Utah 38, Washington State 13
UCLA at Arizona
Prediction: Arizona 37, UCLA 27
BetMGM Line: UCLA -3, o/u: 68.5
Final Score: Arizona 20, UCLA 17
SEC Schedule
– SEC Team-by-Team Schedules & Predictions
Results So Far: SU 31-6, ATS 11-16-1, o/u: 13-16
Click on each game for game preview & prediction
Texas A&M at Arkansas
Prediction: Texas A&M 38, Arkansas 17
BetMGM Line: Texas A&M -23.5, o/u: 57.5
Final Score: Texas A&M 31, Arkansas 27
Northern Illinois at Vanderbilt
Prediction: Vanderbilt 34, Northern Illinois 24
BetMGM Line: Vanderbilt -7, o/u: 54.5
Final Score: Vanderbilt 24, Northern Illinois 18
Ole Miss at Alabama
Prediction: Alabama 55, Ole Miss 10
BetMGM Line: Alabama -37.5, o/u: 61.5
Final Score: Alabama 59, Ole Miss 31
Towson at Florida
Prediction: Florida 48, Towson 13
BetMGM Line: No Line, o/u: No Line
Final Score: Florida 38, Towson 0
Mississippi State at Auburn
Prediction: Auburn 30, Mississippi State 20
BetMGM Line:Auburn -7.5, o/u: 47
Final Score: Auburn 56, Mississippi State 23
Kentucky at South Carolina
Prediction: South Carolina 26, Kentucky 23
BetMGM Line: South Carolina -2.5, o/u: 50.5
Final Score: South Carolina 24, Kentucky 7
Sun Belt Schedule
– Sun Belt Team-by-Team Schedules & Predictions
Results So Far: SU 30-5, ATS 10-15-1, o/u: 13-13
Click on each game for game preview & prediction
Coastal Carolina at Appalachian State
Prediction: Appalachian State 37, Coastal Carolina 30
BetMGM Line: Appalachian State -16.5, o/u: 59.5
Final Score: Appalachian State 56, Coastal Carolina 37
Arkansas State at Troy
Prediction: Troy 37, Arkansas State 30
BetMGM Line: Troy -7.5, o/u: 59.5
Final Score: Arkansas State 50, Troy 43
Louisiana at Georgia Southern
Prediction: Louisiana 34, Georgia Southern 30
BetMGM Line: Louisiana -3.5, o/u: 55.5
Final Score: Louisiana 37, Georgia Southern 24
South Alabama at ULM
Prediction: ULM 34, South Alabama 17
BetMGM Line: ULM -15.5, o/u: 57.5
Final Score: ULM 30, South Alabama 17
Nicholls at Texas State
Prediction: Texas State 34, Nicholls 30
BetMGM Line: No Line, o/u: No Line
Final Score: Texas State 24, Nicholls 3
Week 5 Schedule, Predictions
– ACC, AAC, Big 12, Big Ten
– C-USA, IND, MAC. M-West
