Chinese health authorities have warned people not to travel to the city of Wuhan over concerns a new viral illness that has infected hundreds and killed at least 17 could mutate and spread further.
Some 473 coronavirus cases have been confirmed in 13 jurisdictions, said Li Bin, deputy director of the National Health Commission.
The virus has also spread to Thailand, where four cases have been confirmed, as well as Japan, South Korea, Macau, Hong Kong and the United States, which have all reported one case each.
Officials are working on the assumption the outbreak resulted from human exposure to wild animals being sold illegally at a food market in Wuhan and the virus is mutating, Gao Fu, an academic of the Chinese Academy of Sciences and head of the Chinese Center for Disease Control, told a news conference.
Health minister Baroness Blackwood of North Oxford has announced there will be “enhanced monitoring” of all direct flights from Wuhan to the UK from today.
Catch-up on events as the happened
“There has already been human-to-human transmission and infection of medical workers,” Mr Li said at a news conference with health experts.
“Evidence has shown that the disease has been transmitted through the respiratory tract and there is the possibility of viral mutation.”

Chinese health officials say virus could mutate and spread further as they warn: 'Don't go to Wuhan, don't leave Wuhan'
Some 440 cases confirmed so far as disease reported in Thailand, Japan, South Korea and United States
Everything travellers need to know about coronavirus
‘The risk to travellers to Wuhan from this disease is low and we are not advising them to change their plans’ – Public Health England"There's been some announcements this morning about flights that come direct from the infected region to Heathrow with some additional measures there. This is to ensure that when flights come in directly to Heathrow there is a separate area for people to arrive in."
Further directives are expected to be issued by health minister Matt Hancock later today, including that a team of health workers meet direct flights from Wuhan at Heathrow airport and that inflight announcements are made and leaflets distributed instructing passengers who feel ill to seek assistance from the health team.

Heathrow creates separate arrival area for passengers arriving from coronavirus region
World Health Organization expected to declare international public health emergency“If you are traveling to Wuhan, you should maintain good hand, respiratory and personal hygiene and should avoid visiting animal and bird markets or people who are ill with respiratory symptoms.
"It looks like it doesn't transmit through the air very easily and probably transmits through close contact," he said. "That was not the case with SARS."
The 16 independent experts in disease control, virology, epidemiology and vaccine development held a closed-door meeting at the UN agency's Geneva headquarters.
The tourist from Wuhan came to Hong Kong on Tuesday via high-speed rail from nearby Shenzhen and was detected having fever at the border.
"Yes, of course, the development of a vaccine is underway. Every time we have a mutation [of a virus], we start developing a vaccine immediately," Anna Popova, the head of Rospotrebnadzor, was cited as saying.
RIA cited Elena Yezhlova, head of Rospotrebnadzor's Epidemiological Surveillance Department, as explaining the process.
"The development of a vaccine is a long and complicated process; a decision is made on the basis of risk and the level of need dictated by the current situation," Ms Yezhlova was quoted as saying.
"At present, we will rely on the WHO's recommendations."
"We have preparations, including taking a risky patient from China to our quarantine room and taking them to the hospital via a specially designated ambulance," Fahrettin Koca told the state-owned Anadolu news agency.
"The World Health Organization [WHO] did not recommend thermal cameras for Turkey, but we took all precautions anyway, including thermal cameras."
"The best way to conquer fear is to confront fear," said one commentator on China's Twitter-like Weibo.