Frank Lampard will be looking to build on arguably the biggest win of his Chelsea tenure thus far when Southampton visit on Boxing Day.
A tactical victory over former mentor Jose Mourinho saw Tottenham beaten 2-0 on home soil last time out, Willian netting both in what turned out to be a comfortable win.
Still, it was just the Blues' second win in six and another slip-up will undo the good work done in north London.
Ralph Hasenhuttl's side earned a third win in five with a huge 3-1 away win over relegation rivals Aston Villa in their previous game.
The game is on Boxing Day - Thursday, December 26 - with kick-off at 3pm GMT.
Team news and lineups
Chelsea: Lampard could keep the same team that played so impressively at Tottenham Hotspur Stadium but with the hectic Christmas schedule upon us and a trip to Arsenal on Sunday, the Blues head coach may revert to a back four and freshen up the attacking areas.
Jorginho and Christian Pulisic were left on the bench at Spurs and will be pushing for inclusion while Cesar Azpilicueta may have to be assessed after limping off gingerly although he left the stadium unaided=
Southampton: Kevin Danso is hoping to have overcome a fever to feature in the matchday squad, but Moussa Djenepo's thigh injury is likely to keep him out.
Yan Valery is not expected to return before the new year.
How we think the sides could line up…
Chelsea: Kepa, James, Rudiger, Zouma, Azpilicueta; Kante, Jorginho, Kovacic; Willian, Abraham, Pulisic.
Southampton: McCarthy, Cedric, Stephens, Bednarek, Bertrand, Armstrong, Ward-Prowse, Hojbjerg, Redmond, Long, Ings
How to stream and watch on TV
Every single Premier League match in gameweek 19 will be shown live on Amazon Prime, while there will also be a dedicated goals centre for every goal from every game.
Existing and new Prime members can watch on devices using the Prime Video app, across mobile, Fire TV, games consoles, Virgin’s V6 TV Box, BT TV, TalkTalk TV, Apple TV, Chromecast, online and more - and Virgin will show select matches in 4K. Click here for more details.
Amazon Prime is available for £7.99 per month/£79 a year, but you can also watch any game for free this week if you start a 30-day free trial of Amazon Prime.
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Betting tips and odds
Match odds
- Chelsea to win: 1/3
- Draw: 9/2
- Southampton to win: 8/1
Odds provided by Betfair. Click here to place a bet.
Match prediction: Chelsea 2-0 Southampton
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Head to head (H2H) history and results
Chelsea dominate this Premier League fixture with 24 wins in 41 meetings, along with nine draws and just eight defeats.
The Saints picked up a goalless draw at the Bridge last season, but the Blues have already beaten them 4-1 at St Mary's this term.