Gonzalo Higuain is set to make his Premier League debut as Chelsea travel to AFC Bournemouth on Wednesday.
Higuain made his Blues bow in Sunday's FA Cup win over Sheffield Wednesday, when Eden Hazard was rested, but the Belgian is poised to return as one of a raft of changes.
David Luiz, N'Golo Kante and Jorginho are likely to return, while Callum Hudson-Odoi, who is yet to start in the Premier League, could find himself on the bench once more.
Provisional squad: Kepa, Caballero, Rudiger, Alonso, Jorginho, Kante, Barkley, Higuain, Hazard, Pedro, Loftus-Cheek, Kovacic, Hudson-Odoi, Giroud, Zappacosta, Willian, Christensen, Azpilicueta, Luiz, Emerson Palmieri, Ampadu, Hudson-Odoi.