Chelsea were rewarded for their 2-0 victory over Stoke City in the FA Cup sixth round with a tough semi-final tie against Aston Villa.
Villa fought back from 2-0 down to defeat Reading 4-2 to reach the semi-final, their second appearance at Wembley this season after their Carling Cup final defeat.
"I think at this stage any tie will be tough," said the Chelsea assistant manager Ray Wilkins after the draw.
In the other semi-final Portsmouth will face the winner of the replay between Tottenham and Fulham.
The Spurs manager Harry Redknapp now has the incentive of a possible semi-final meeting with his former side whom he led to FA Cup glory in 2008.
The ties will be played on the weekend of 10 and 11 April at Wembley Stadium.