Altior won his second successive Betway Queen Mother Champion Chase - equalling the all-time record for 18 consecutive victories over jumps.
De Boinville had Henderson's brilliant two-miler in a prominent position throughout, chasing the pace set by Saint Calvados.
The field packed up behind Altior going to the last as Sceau Royal and eventual runner-up Politologue challenged on either side.
However, the nine-year-old - who had made an early mistake at the water jump - dug deep to prevail by one and three-quarter lengths and the same at odds of 4-11.
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