Carlton's own soap star James Hooton says he 'may not be taking a Covid vaccine' because he is "pro immune system and pro informed choice".
The Emmerdale actor, who has played caretaker Sam Dingle in the ITV series since 1995, prompted a debate on Twitter following his remarks.
Mr Hooton, 47, who grew up in Carlton, revealed his might not take a vaccine for coronavirus in a tweet posted on April 14.
His tweet has since been liked more than two-thousand times, and retweeted hundreds of times, but his comments have caused a divide.
In the tweet he said: "I’m 47yrs old.
"I take Vit c,d, zinc, b-12, Q10 and anti virals such as Andrographis, Sambucus, Curcumin, along with regular exercise and a varied diet.
"I may not be taking a Covid vaccine. I may be labelled “anti vaxer” for being pro immune system, pro informed choice."
Some of his fans and followers said they were "disappointed", while others supported his statement.
His comments come as vaccine uptake in Nottingham was revealed to be one of the lowest outside the London boroughs last week.
Public health officials said it was "disappointing" and are now calling on those who are eligible to get their jab when called up.
A new vaccination bus is now also travelling around the city to increase uptake and quash any fears, conspiracies or concerns over the vaccine.
