Police are investigating a violent incident following Hibs’ friendly match away at Carlisle on Tuesday night.
The Carlisle News and Star reports that the arrests were made later on at night in the city following the game.
Hibs came back from 3-1 down to win the match 4-3, with 1,065 away supporters making the journey to Cumbria.
The incident is reported to have happened around 9.30pm on Warwick Road as a group of Hibs fans headed towards Eldred Street.
The victim was with three other friends, wearing a white Elise t-shirt and a black jacket. One friend had blond hair and wore a bright green jacket.
"Anyone who witnessed this group of visiting supporters being attacked should please contact PC 2050 Black," said a police spokeswoman, urging witnesses to call 101 if they can help.
A public order offence is also investigated which happened around half-an-hour later.
A spokesman from Cumbria Police said: "We were called at about 10pm to the report of public order on Botchergate, Carlisle.
"A 26-year-old man from East Lothian was arrested on suspicion of a public order offence and remains in police custody.
"A 49-year-old man from Edinburgh was arrested on on Cecil Street on suspicion of assault and remains in police custody."
Hibs face English opposition once more this pre-season when Newcastle Utd visit Easter Road at the end of July.
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