The 2021 schedule is out for the Arizona Cardinals and they will open the season on the road against the Tennessee Titans, the AFC South champs last season. They have not faced the Titans since 2017.
According to BetMGM, Arizona opens as underdogs on the road in the season opener.
The Titans are favored by 2.5 points for bets against the spread.
On the money line, betting for an outright winner, the Titans are favored at -140 (bet $140 to win $100). That gives Tennessee 58.33% implied odds of winning.
The Cardinals are the underdogs to win straight up at +115 (bet $100 to win $115). They have 46.51% implied odds of winning.
The total for the game is set at 51.5 points.
The Cardinals went 8-8 overall last season and were 4-4 on the road. They went 7-9 against the spread (ATS) and 5-11 O/U (over/under the total)
Tennessee was 11-5 last year and 5-3 at home. They were 7-10 ATS and 12-4-1 O/U.
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