Brunel academics have announced a one-day strike on Tuesday claiming they are being "bullied" into redundancy.
The Association of University Teachers also announced it will adopt further industrial action short of a strike until the university ensures members there will be no compulsory redundancies.
The dispute, on-going since September, is over plans by the vice-chancellor, Steven Schwartz, to cull jobs in a bid to re-position the university as a research-led institution in time for the next research assessment exercise.
Lecturers will not take part in student assessment, staff evaluations or appraisals until they are guaranteed there will be no compulsory redundancies.
AUT members at the university have been told they will lose a day's pay for the strike and for every day they take industrial action.
The university insists that it is negotiating redundancies on a case-by-case basis and is hoping to avoid any compulsory redundancies. None have so far been issued.
Speaking at the AUT conference in Eastbourne shortly after the announcement late yesterday afternoon, Peter Mitchell, the assistant general secretary, said: "The vice-chancellor is failing to negotiate on the threat of compulsory redundancies.
"It amounts to bullying and harassment of staff. They [the university management] are escalating this dispute. The action will be continuous until they withdraw the threat of compulsory redundancies."
He added that the union believed key AUT activists were being targeted by the university management.
Prof Schwartz told EducationGuardian.co.uk that he "completely disagreed" with the allegations of bullying and harassment, and that management was targeting activists.
"Obviously we're quite disappointed. We would prefer that they didn't [strike]. We haven't made anyone [compulsorily] redundant. It's premature and we hope they will recognise that," he said.
"We hope that we will resolve these matters as soon as possible."