A middle-aged man from the UK could have been the first to have died from a vaping-related illness.
13 people in the USA have died from unexplained conditions relating to vaping and more than 800 have fallen ill.
Now, Glynis Miller says her husband Terry was the first to die from the condition and she has called for a new inquest.
Terry died in 2010 after developing lipoid pneumonia - a rare condition that occurs when fat particles enter the lungs, reports The Mirror .
The inquest heard that oil from vaping liquid was found in his lungs, but the original inquest recorded an open verdict.
Wife Glynis blames vaping for Terry's death and says he would have been better off smoking.
She says Public Heath England did not have enough evidence at the time of the original inquest to back up the claim about the risks of e-cigarettes.
The case was highlighted after a report from the Medicines and Healthcare Products Regulatory Agency said vaping hit the health of 200 British e-cigarette users.
Glynis said: "The doctor took me into a room as Terry's condition deteriorated and told me he was as certain as he could be that it was caused by the e-cigarette.
"People ask, do you think vaping caused his death? I can't say definitively that it did, only that it very much contributed.
"If he hadn't used the e-cigarette and carried on smoking, I don't think he'd have died at the age of 57."
NHS Professor John Newton said: "It isn't risk-free but it is far less harmful than smoking.
"It would be tragic if smokers who could quit with the help of an e-cigarette did not do so because of false fears about their safety."
Experts are now calling for a national system to record every problem associated with e-cigarettes amid increasing concern over their safety, according to The Sunday Times.
They have already been banned in Brazil, India, Thailand and Singapore.
