West Ham's European hopes hang on a string but missing out on Europe should not overshadow an incredible season for David Moyes.
The Irons are 11/8 favourites with Betfred while Brighton are 2/1 and a draw is 12/5.
The Albion will be without top scorer Neal Maupay and captain Lewis Dunk which will benefit David Moyes' side greatly when they face a weakened Graham Potter side.
However, they will have a challenge on their hands if recent meetings are anything to go by.
Since Brighton were promoted to the Premier League, they have won three and drawn four - never failing to score against West Ham.
They have become a bogey team for the London club but with European football at stake, this might be the motivation they need to break their winless run against the south coast club.
Tips
18+ | Gamble responsibly | begambleaware.org | Odds subject to change
West Ham need points to keep their top four hopes alive but the Hammers face a Brighton side who have never failed to score against them in the Premier League.
So with that in mind and Brighton losing key defender Lewis Dunk, it is fair to assume both sides will find the net at 8/11.
Now to need points you need goals, they need goals you will need Jesse Lingard.
The playmaker has been involved in seven goals in the last seven Premier League matches.
However, he has missed the mark in the last three games meaning he is overdue a goal given his recent form.
A goal against his former side will sweeten the deal on the road to Europe.
