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The Independent UK
The Independent UK
National
Vishwam Sankaran

Breakthrough discovery could slow or reverse Parkinson’s disease

  • A new study suggests that a low-oxygen environment, similar to the air around Mount Everest’s base camp, could be key to treating and potentially reversing Parkinson's disease.
  • Research indicates that Parkinson's symptoms are linked to an accumulation of excess oxygen molecules in the brain, caused by dysfunctional cellular processes.
  • In experiments, mice with Parkinson's-like conditions housed in low-oxygen chambers did not experience neuron loss or movement problems, despite developing protein clumps.
  • The findings suggest that reducing overall oxygen supply protects brain cells from damage, even if it does not prevent the formation of toxic protein clumps.
  • Scientists are now working on "hypoxia in a pill" drugs to mimic these low-oxygen effects, though further research is required before human application.

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