Three police officers were injured after a gang of 50 people threw fireworks and other missiles at them.
Police were called to a report that a female officer had been assaulted on Moston Lane, Moston, just before 9.30pm last night (November 5).
Shortly after officers arrived, large groups of people starting throwing fireworks and other missiles at them, resulting in more patrols being sent to the scene.
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Extra patrols were deployed to Penn Street and Ebsworth Street and the surrounding areas of Moston to disperse the groups.
One man has been arrested on suspicion of affray, and another man was arrested on suspicion of two counts of assaulting an emergency worker and affray, GMP said.
A dispersal order was put in place around Moston until 6.30am this morning
Superintendent Helen Critchley, of GMPs City of Manchester district, said: "This has been a large scale disturbance involving a number of people throwing missiles not only at officers but at members of the public.
"In response to this disorder we have dispatched a large number of officers to the scene and we now have a dispersal order in place until 6.30am tomorrow morning. Officers will be remaining in the area over night as a precaution.

"This has been a multi-agency response from police, fire and the ambulance service and I would like to thank our emergency services colleagues for their assistance this evening.
"I would also like to thank members of the public for their patience while we continue to deal with this incident.
"As a result of this incident three officers have sustained injuries, thankfully these are minor injuries due to the quick response of their colleagues.
"GMP will not tolerate violence towards officers in the course of their duties".
Anyone with information regarding this incident should contact police on 101 quoting incident 3221 of 31/101/21.

Alternatively, details can be passed via our online live webchat function at www.gmp.police.uk.
Reports can also be made anonymously via the independent charity Crimestoppers on 0800 555 111.