Three children and another pedestrian have been hit by a vehicle in Carluke.
Emergency services including 10 ambulances raced to the scene at the junction between James Street and Kirkton Street at around 3.10pm.
All four casualties are currently being treated at the Queen Elizabeth University Hospital in Glasgow, but the extent of their injuries are not known at present.
Road diversions are in place and anyone with information is asked to contact police who have launched an urgent appeal.
Inspector William Broatch told Lanarkshire Live: “Around 3.10pm, police were called to James Street in Carluke, at the junction with Kirkton Street, following a report of a road crash involving a car and four pedestrians - a woman and three children.
"The pedestrians are all being conveyed to hospital for treatment.
"Emergency services remain at the scene and local diversions are in place."
Anyone with any information is asked to call police on 101. Information can also be left anonymously via Crimestoppers on 0800 555 111.
A Scottish Ambulance Service spokesperson said: "We received a call at 15:07hrs to attend an incident on Kirkton Street, Carluke and dispatched 10 resources to the scene.
"One female in her 20s and three children have been transported to the Queen Elizabeth University Hospital, Glasgow."
South Lanarkshire Council have advised they are assisting Police Scotland over the incident and will do everything they can to help.
Meanwhile, Clydesdale MSP Màiri McAllan has shared her concern for those involved in the accident.
She posted on Twitter: "I am deeply worried about reports from Carluke this afternoon.
"My team have been in touch with police offering all our support.
"I want to thank the emergency services on the scene and in the meantime am, like everyone, praying for good news that no one is seriously hurt."
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