Boris Johnson is to chair an emergency Cobra meeting in response to Storm Christoph.
Communities are braced for flooding as Storm Christoph brings “significant” rainfall across most of the UK.
The majority of England, Wales and Northern Ireland are subject to amber and yellow weather warnings until at least midday on Thursday.
Major incidents have already been declared in Greater Manchester and South Yorkshire amid amber and yellow weather warnings for the storm, which could also bring snow to northern areas.
Prime Minister Boris Johnson told the Commons: “Our sympathies also go out to those affected by the latest floods.
“I want to thank the Environment Agency and our emergency services for the work they’re doing to support those communities, and I’ll be chairing a Cobra meeting later on to co-ordinate the national response."
The amber alert warns of the risk of flooding and deep floodwaters which could pose a risk to life, and there are further yellow warnings for snow and ice in Scotland.
Met Office forecaster Grahame Madge described Christoph as “quite a slow-moving system” which is bringing “a variety of weather” to the UK.
The meteorologist said: “While rain remains the main hazard in the south, further north we’ve got snow and ice remaining a risk.
“The system will work its way through, we are expecting significant totals of rainfall and when you combine that with snowmelt it can lead to localised flooding across the affected regions.”
It isn't yet known when the meeting will be held.
