Boris Johnson declared the terms 'Leave' and 'Remain' defunct as he prepared to ram his Brexit bill through Parliament.
The PM has angered some MPs by stripping measures to hand more control to Parliament over the Brexit process out of the bill now that he has a strong majority.
Mr Johnson, moving the European Union (Withdrawal Agreement) Bill at second reading, urged Parliament to come together and allow the "warmth and natural affection that we all share" for the UK's European neighbours to "find renewed expression in one great new national project".
Speaking in the Commons, Mr Johnson said the Bill must not be seen as a victory for one party or faction before adding: "This is the time when we move on and discard the old labels of Leave and Remain.
"In fact, the very words seem tired to me - as defunct as Big-enders and Little-enders, or Montagues and Capulets at the end of the play.
"Now is the time to act together as one reinvigorated nation, one United Kingdom, filled with renewed confidence in our national destiny and determined at last to take advantage of the opportunities that now lie before us."
MPs will vote on the bill this afternoon. It's expected to pass easily.
Labour's Lisa Nandy also questioned the Prime Minister's reluctance to help child refugees.
Ms Nandy said that while the Prime Minister is right to say he has won a mandate to get Brexit done, he has "not earned the right to shoehorn into this legislation measures that are a direct attack on some of the most vulnerable children in the world".
She added: "If he thinks that people in towns like mine who believe that we should deliver Brexit want to see us turn our back on decency and tolerance and kindness and warmth and empathy, he is wrong. Will he take these measures on child refugees out of this Bill?"

Mr Johnson replied: "She is wrong on this point. We remain absolutely committed to ensuring that we continue in this country to receive unaccompanied children, as we have done."
Mr Corbyn said "shame on this Government" after sections of the Bill relating to offering sanctuary to orphans and unaccompanied children were removed.
He added: "I now move on to what I think is one of the most appalling sections of this Bill and what the Prime Minister has presented to us this morning.
"I want to make it clear that I see the Government's removal of the protection in this Bill for unaccompanied children seeking asylum is nothing short of an absolute disgrace and a piece of dishonesty toward those people who, at the moment, are clearly very, very concerned."
He added: "Throughout the last Parliament, and for his whole life, and I was talking to him last night, my good friend Lord Dubs has worked tirelessly to ensure children affected by the worst aspects of global injustice can be given sanctuary in this country.
"Now this Government in its first week in office has ripped up those very hard-won commitments."
He added: "I simply say this: coming to up to Christmas shame on this Government for abandoning children in this way."