Boris Johnson appeared to call Jeremy Corbyn a "big girl's blouse" over the Labour leader's refusal to support his desire for a general election.
The comments, which will are likely to prompt accusations of sexism, came just minutes after the prime minister branded Labour's economic plans "s**t or bust" during a back and forth with Mr Corbyn in a bruising PMQs session.
"Call an election, you great big girl's blouse," Mr Johnson appeared to say in the Commons on Wednesday.
It came during an ill-tempered PMQs in which Mr Corbyn grilled Mr Johnson to provide evidence he was making any progress in Brexit negotiations with the European Union.
"We are less than 60 days away from leaving the EU with no deal. The prime minister has had two days in office before the summer recess and then planned to prorogue parliament," Mr Corbyn had said before Mr Johnson's outburst.
"Yesterday, he lost one vote, his first vote in parliament. He now wants to dissolve parliament. He's desperate, absolutely desperate to avoid scrutiny."
Mr Johnson faced the questions just hours after suffering a humiliating defeat when nearly two dozen of his own MPs rebelled to help the Commons wrest control of the parliamentary order paper.
They are attempting to pass a bill that would block Mr Johnson from taking the UK out of the EU without a deal.
Downing Street has been contacted for comment.
