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The Independent UK
The Independent UK
National
Storm Newton

Blood test could revolutionise the way Alzheimer’s is diagnosed

  • New research suggests a simple blood test could identify signs of Alzheimer's disease decades before symptoms manifest.
  • A study in The Lancet found that high levels of amyloid and p-tau217 biomarkers in midlife were linked to poorer cognitive performance over five years.
  • These findings indicate that Alzheimer's neuropathology can be present in midlife, supporting the concept that the disease begins long before clinical symptoms emerge.
  • A separate study proposed a novel brain scanning technique, MK6240, which proved more effective at detecting tau protein tangles earlier than existing methods.
  • Experts believe earlier detection through blood tests could revolutionise diagnosis, facilitate participation in clinical trials, and improve access to disease-modifying treatments, with a goal to make them available on the NHS by 2029.

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