All eyes will be on Anfield on Wednesday evening as the Premier League's top two clash on Merseyside.
Following Tottenham's 1-1 draw away at Crystal Palace on Sunday afternoon, Liverpool missed the chance to go top after they could only record the same scoreline at struggling Fulham.
Jurgen Klopp's men were dealt some more bad injury news in the match and it could open the door for Jose Mourinho's side to grab a win at Anfield and open up a three-point lead over the reigning champions.
The Spurs boss knows exactly how to approach these games and he will undoubtedly have a plan up his sleeve to ensure the Lilywhites return to the capital with the points.
But who should start for Spurs against Liverpool?
We’ve asked our Tottenham writers at football.london to give their thoughts on who should be in Mourinho's XI on Wednesday evening for the crunch clash. Here is what they had to say:
Rob Guest - Tottenham Hotspur reporter
The main call Mourinho has to make on Merseyside is whether or not he starts Tanguy Ndombele or Giovani Lo Celso in midfield.
The pair have often swapped late in matches this season with the Argentine usually the man to come on, yet he may decide to switch things up against Klopp's men.
However, the fact Ndombele has a bit of an X-factor to his game should see him start as he has the potential to create that one bit of magic that could settle this fixture.
The rest of the team picks itself at present so that means an unchanged XI from Sunday's draw at Crystal Palace.
Given Liverpool's recent injuries at the back, it would be nice to see Steven Bergwijn attack a bit more as he also has the quality to punish them.
Guest's team: Lloris; Aurier, Alderweireld, Dier, Reguilon; Hojbjerg, Sissoko, Ndombele; Bergwijn, Son, Kane.
James Piercy - football.london content editor
These are precisely the sort of games Jose Mourinho revels in as the chance to a) restrict and out-think and, hopefully then, b) beat the defending champions and one of the best attacking teams in the world, will be an appealing challenge for the Portuguese.
Assuming Spurs adopt a similar system as was successful against Manchester City and then stifled Chelsea, Mourinho will likely play a 4-2-3-1 and, unlike at Stamford Bridge, will have his first choice centre-back pairing in Eric Dier and Toby Alderweireld.
The rest of the defensive unit picks itself, unless he feels Matt Doherty may be fresher than Serge Aurier which could be considered on the right.
The only real dilemma, essentially, is in centre-midfield and which combination of Pierre-Emile Hojbjerg, Tanguy Ndombele, Moussa Sissoko and Giovanni Lo Celso he opts for.
Ndombele’s withdrawal against Crystal Palace was smart as the Frenchman is perfect for breaking the Liverpool press, and assuming Sissoko and Hojbjerg have the energy in their legs – after a pretty relentless schedule – then it should probably stay the same.
Piercy's team: Lloris; Doherty, Dier, Alderweireld, Reguilon; Hojbjerg, Sissoko; Bergwijn, Ndombele, Son; Kane