A woman is dead after a two-vehicle crash on the Barton Highway that closed the main road in both directions near Murrumbateman.
The crash occurred on the Barton Highway near Gounyan Road, just north of Murrumbateman, and was first reported on Thursday morning at about 6.10am.
The 38-year-old woman, who was driving a Kia, died at the scene.
Emergency services and the crash investigation unit are at the scene and police investigations are expected to take some time.
The 31-year-old male driver of a Toyota Hilux was trapped in his ute before being freed by Fire and Rescue NSW.
He was airlifted to Canberra Hospital in a serious but stable condition.
Officers attached to the Hume Police District established a crime scene, which will be examined by specialist forensic police.
An investigation into the circumstances surrounding the crash is underway
A report will be prepared for the information of the Coroner.
Police are seeking any witnesses, including motorists with dashcam vision to call Yass Police on 02 6226 9399 or Crime Stoppers on 1800 333 000.
Police re-opened the highway at around 12.40pm after being closed for nearly six hours.
