Avanti, Northern and CrossCountry train services are delayed this morning after a tree fell onto the railway line.
Stormy weather uprooted the tree on Wednesday evening and it has caused damage to the over-head electrical wire near to Adlington, in Cheshire.
Trains are unable to run between Stockport and Stoke-on-Trent, as well as between Macclesfield and Wilmslow, as a result.
Engineers are carrying out repairs, but a number of early morning services between Manchester Piccadilly, London Euston, Stoke-on-Trent and Macclesfield have been cancelled or delayed.
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The disruption is expected to continue until 10am on Thursday morning.
Replacement shuttle buses have been set off for affected passengers.
Passengers on Avanti services can travel on a bus service between Macclesfield and Wilmslow, while a bus between Stoke-on-Trent and Wilmslow has been arranged for CrossCountry travellers.
A bus service between Stockport and Macclesfield, as well as Stockport and Stoke, has been arranged for Northern passengers.
The Manchester Piccadilly Twitter account shared pictures of the damaged wires this morning.
A tweet from the account said: "Due to damage to the overhead wires between Poynton and Adlington (Cheshire) there are cancellations and alterations to services this morning.
"@Northernassist are providing rail replacement coaches between Stockport and Stoke, in both directions for intermediate stops, passengers may travel on @northernassist or @CrossCountryUK services to Stockport and change.
"@AvantiWestCoast and @CrossCountryUK services are diverting via Wilmslow and have rail replacement services for Macclesfield and Stoke."
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