At least 20 people have been found dead in a nightclub in South Africa's East London city, according to officials.
The bodies were discovered at the Enyobeni Tavern early on Sunday, and reports say several people were injured.
"The circumstances surrounding the incident are under investigation as we speak," a police spokesman told the Newzroom Africa television channel.
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"We do not want to make any speculations at this stage," Brigadier Tembinkosi Kinana said.
A large number of emergency service vehicles have been are currently at the scene.
Reports say that relatives of the victims have been unable to see their bodies.
Locals have now called for the venue to be closed.
Eastern Cape Police Commissioner Nomthetheleli Lilian Mene told SABC News that "there was an alleged stampede inside the tavern".
However, this has not been verified.
Four people have been taken to hospital, SABC reports.
Brigadier Kinana told reporters most of those found dead were young adults aged between 18 and 20.
Eyewitnesses told the Daily Dispatch newspaper that bodies were lying inside the venue as if they had collapsed on the floor, with some reporting potential poisoning.
A spokesperson for Eastern Cape's health department told News24 the dead bodies were taken to various nearby mortuaries.
Siyanda Manana added: "We are going to conduct autopsies as soon as possible to establish the probable cause of death."
South Africa's Minister of Police Bheki Cele was on his way to the Eastern Cape with an additional team of experts to help with investigations, the province's premier Oscar Mabuyane said.
"We can't believe it... Young people who were not sick, young people who should be with their families enjoying their winter holidays - they just have lost their lives like that," he added.
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