At least 165 people diagnosed with the Covid-19 virus have now died in hospitals across Greater Manchester, the NHS said on Friday.
Twenty-five more deaths have now been recorded, NHS England data published today showed.
On Thursday, the figure was at least 140.
In the UK, there have been a total of 3,605 coronavirus deaths in hospitals - an increase of 684 people compared to NHS statistics published on Thursday.
It's the highest day-on-day rise since the outbreak began.
Some of the larger trusts run several hospitals in Greater Manchester.
Manchester University NHS Foundation Trust oversees the Manchester Royal Infirmary (MRI), Wythenshawe Hospital and Trafford General, while Pennine Acute is in charge of North Manchester General Hospital, Fairfield Hospital, the Royal Oldham Hospital and Rochdale Infirmary.
NHS England figures were published for each hospital trust.
More people have died at Salford Royal Hospital than at any other in the region.
All but one trust - The Christie NHS Foundation Trust - recorded an increase in deaths on Friday.
Five more patients died at the Royal Bolton Hospital, four within Manchester University NHS Foundation Trust; four within the Pennine Acute hospitals; six at Salford; one at Stockport NHS Foundation Trust; three at Tameside and Glossop and two more at Wrightington, Wigan and Leigh NHS Foundation Trust.
They show the death toll at each of our hospital trust as follows:
Bolton NHS Foundation Trust - 13.
Manchester University NHS Foundation Trust - 34.
Pennine Acute Hospitals NHS Trust - 29.
Salford Royal NHS Foundation Trust - 44.
Stockport NHS Foundation Trust - 15.
Tameside and Glossop Integrated Care NHS Foundation Trust - 21.
The Christie NHS Foundation Trust - 1.
Wrightington, Wigan and Leigh NHS Foundation Trust - 8.
The Department of Heath and Social Care said as of 9am on Friday, 173,784 people have been tested for coronavirus.
Of those, 38,168 tested positive.
The figures do not include deaths outside hospital, such as those in care homes.
In England alone, the reported deaths in hospitals now stands at 3,302.
The NHS said: "A further 604 people, who tested positive for the Coronavirus (Covid-19) have died, bringing the total number of confirmed reported deaths in hospitals in England to 3,302.
"Patients were aged between 24 and 100 years old. 34 of the 604 patients (aged between 27 and 92 years old) had no known underlying health condition.
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"Their families have been informed."
The latest figures were revealed as Buckingham Palace confirmed the Queen will address the nation over coronavirus in a recorded televised broadcast at 8pm on Sunday.
The rare broadcast, recorded this week at Windsor Castle, was called 'a special broadcast to the United Kingdom and the Commonwealth' by the palace.
