Get all your news in one place.
100’s of premium titles.
One app.
Start reading
Reuters
Reuters
Business

AstraZeneca lupus drug fails to meet main goal in study

(Reuters) - AstraZeneca's experimental drug anifrolumab failed to meet its main target in a late-stage clinical study treating patients with moderate to severe lupus, the British drugmaker said on Friday.

AstraZeneca said the drug did not meet the main goal in the final-stage of one of the two clinical trials under the TULIP program, failing to show "statistically-significant" reduction in disease activity in patients with systemic lupus erythematosus, commonly known as SLE.

"The result of this trial is disappointing for patients and the lupus community," said Sean Bohen, AstraZeneca's Chief Medical Officer.

AstraZeneca has been in a race with GlaxoSmithKline and French biotech company Neovacs to create new treatments for lupus, which affects about 5 million people globally.

Anifrolumab, which is given intravenously, is designed for patients with moderate to severe lupus and works in a different way to GlaxoSmithKline's Benlysta by targeting interferon, a protein involved in inflammation.

(Reporting by Justin George Varghese in Bengaluru; editing by Amrutha Gayathri and Patrick Graham)

Sign up to read this article
Read news from 100’s of titles, curated specifically for you.
Already a member? Sign in here
Related Stories
Top stories on inkl right now
One subscription that gives you access to news from hundreds of sites
Already a member? Sign in here
Our Picks
Fourteen days free
Download the app
One app. One membership.
100+ trusted global sources.