After earning a point at Norwich, it will be intriguing to see what changes Freddie Ljungberg makes for his second game in charge.
Hector Bellerin is pushing to make a return from injury, but you would think Calum Chambers may keep his place at left-back.
Kieran Tierney and Rob Holding could be added to the defence, though, while Lucas Torreira will hope to start in midfield against Brighton after impressing off the bench against Norwich.
It is further forward where the greatest interest lies, however, as Ljungberg mulls over how to get the best out of his attacking options.
The Swede went with a 4-3-3 formation against Norwich - deploying Alexandre Lacazette, Mesut Ozil and Pierre-Emerick Aubameyang in a front three.
It is likely the trio will get another chance to sign, but Gabriel Martinelli is surely in contention to start given his fine form.
The Brazilian could come in to play out wide, shifting Ozil into the No.10 role and dropping one of Granit Xhaka or Matteo Guendouzi as part of a 4-2-3-1 formation.
Predicted Arsenal lineup (4-2-3-1): Leno; Chambers, Holding, Luiz, Tierney; Torreira, Xhaka; Aubameyang, Ozil, Martinelli; Lacazette.
