Out-of-form Arsenal will be without Aaron Ramsey for tonight's Europa League semi-final first-leg tie against Valencia.
The Juventus-bound midfield stalwart sustained a hamstring problem during the last-eight meeting with Napoli and there had been growing fears over the past few days that the issue would force him to miss the rest of the season.
Unai Emery confirmed those suspicions in his pre-match press conference, with a small tear to the muscle meaning that Ramsey has played the final game of his 11-year Arsenal career before a summer switch to Serie A.
Denis Suarez's ineffectual loan spell with the Gunners - who have lost each of their last three Premier League matches - has been curtailed by a persistent groin complaint, while long-term absentees Danny Welbeck (ankle), Rob Holding and Hector Bellerin (both knee) remain out.
However, Mesut Ozil is in line to return after missing the 3-0 defeat at Leicester with a bruised foot, while Nacho Monreal should be fit to start following a calf injury.
Petr Cech is expected to replace Bernd Leno for Europa League duty as usual, while Laurent Koscielny is likely to return as part of a back three.
Former Arsenal defender Gabriel Paulista should line up for Valencia on Thursday, but another ex-Gunner - Francis Coquelin - is suspended after picking up a booking in the quarter-final, second-leg win over Villarreal.
Denis Cheryshev (knee) and Geoffrey Kondogbia (thigh) are also sidelined for the visitors.
Predicted line-ups:
Arsenal XI (3-4-1-2): Cech, Sokratis, Koscielny, Monreal, Maitland-Niles, Xhaka, Torreira, Kolasinac, Ozil, Aubameyang, Lacazette
Valencia XI (4-4-2): Neto, Piccini, Garay, Gabriel, Gaya, Soler, Wass, Parejo, Guedes, Rodrigo, Gameiro
