Arsenal will be sweating on the fitness of captain Laurent Koscielny ahead of Sunday's Premier League visit of Southampton.
The defender limped off during Thursday's 3-0 Europa League win over BATE Borisov and could miss the clash against struggling Saints.
Striker Alexandre Lacazette is available after missing that victory through suspension while midfielder Ainsley Maitland-Niles will be hoping to overcome illness to be involved as forward Danny Welbeck (ankle), right-back Hector Bellerin and defender Rob Holding (both knee) remain sidelined.
Meanwhile, Southampton's teenage forward Michael Obafemi will be in contention.
The 18-year-old, who has not featured since December 22, has returned to training following a thigh injury.
Midfielder Mario Lemina (abdominal) and striker Danny Ings (hamstring) remain unavailable to Saints boss Ralph Hasenhuttl.
Arsenal vs Southampton line-ups: Predicted XIs
Arsenal XI: Leno; Maitland-Niles, Mustafi, Koscielny, Kolasinac; Xhaka, Torreira, Guendouzi, Ramsey, Aubameyang, Lacazette
Southampton XI: McCarthy, Valery, Bednarek, Yoshida, Vestergaard, Bertrand, Hoijbjerg, Ward-Prowse, Armstrong, Redmond, Long
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