With only 48 hours between the Aston Villa game and this tie, Unai Emery will make a raft of changes to the Arsenal side.
Mesut Ozil, Reiss Nelson and Gabriel Martinelli are all likely to get a game, as is Rob Holding.
We spoke to Andy Ha ahead of the match at the Emirates Stadium:
Recommended bets:
Win, lose or draw?
There should be enough quality on the pitch to reach the next round - with an Arsenal win at 2/5 .
A 3-1 win to Arsenal at 9/1 will be enough.
First goalscorer?
Tyreece John-Jules or Gabriel Martinelli will lead the line for the Gunners, and I would fancy one of them to open the scoring.
Martinelli to score first is 5/1 for Emery's side.
First card?
Lucas Torreira should start after being benched at the weekend, and the fiesty Uruguayan is always good for a booking.
Who is on penalties?
A tricky one, given Pierre-Emerick Aubameyang and Nicolas Pepe will likely be given the night off. Reiss Nelson could grab the ball if Arsenal are given a spot kick.
Nelson is 13/2 to score first or 9/5 anytime should he feature tonight.
Will you keep a clean sheet?
Forest will probably score, let's be honest. No clean sheet for Arsenal is priced at 1/2 with thepools.com so I'm pretty sure they will concede.
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