Kieran Tierney was handed his Premier League debut for Arsenal as Unai Emery named Nicolas Pepe, Pierre-Emerick Aubameyang and Alexandre Lacazette in attack against Crystal Palace.
The Gunners made nine changes from their 3-2 Europa League victory over Vitoria as Pepe was rewarded with a start having come off the bench to score twice.
Tierney signed from Celtic in the summer but was recovering from a groin injury and, having worked his way back to fitness, he has now been deemed ready to make his Premier League bow.
Lacazette is also back from an ankle problem and looked rusty against Vitoria but retained his place against the Eagles.
Wilfried Zaha started for the visitors having been heavily linked with a summer move to the Emirates Stadium.
Andros Townsend came in as Roy Hodgson made only one alteration from the 2-0 defeat to Manchester City and Jeffrey Schlupp dropped to the bench.
Starting line-ups:
Arsenal: Leno, Chambers, Papastathopoulos, Luiz, Tierney, Guendouzi, Xhaka, Pepe, Ceballos, Aubameyang, Lacazette.
Subs:Bellerin, Torreira, Holding, Martinez, Kolasinac, Martinelli, Saka.
Crystal Palace: Hennessey, Ward, Tomkins, Cahill, van Aanholt, Townsend, Kouyate, Milivojevic, McArthur, Zaha, Ayew.
Subs: Dann, Meyer, Schlupp, Benteke, Henderson, McCarthy, Kelly.
