Arsenal pair Kieran Tierney and Hector Bellerin are not fit to face Aston Villa, despite being back in training, but enjoyed a run out with the Under-23s on Friday night.
Fellow defender Rob Holding travelled to Germany for Thursday night's Europa League meeting with Frankfurt as he nears a return, though he did not feature in the matchday squad.
Emery used that game to rotate his squad, with Shkodran Mustafi, Emiliano Martinez, Bukayo Saka and Emile Smith Rowe all making their first starts of the season. French forward Alexandre Lacazette is out until October with an ankle injury.
The visitors could have Matt Targett back from a thigh injury, but Jonathan Kodjia and James Chester are still out. Trezeguet is back from suspension.
Predicted lineups
Arsenal XI: Leno, Maitland-Niles, Sokratis, Luiz, Kolasinac, Xhaka, Ceballos, Guendouzi, Nelson, Aubameyang, Pepe.
Aston Villa XI: Heaton, Guilbert, Engels, Mings, Taylor, Luiz, Grealish, McGinn, El Ghazi, Trezeguet, Wesle
