The holders will fancy their chances of reaching the last eight but this is by no means a straightforward assignment. Boro come in to this tie on the back of five successive league wins and buoyed by their stunning 2-0 win over Manchester City in the last round. Gabriel could make his debut at the back and Wojciech Szczesny will return in goal – with the Gunners the only side still fighting in the Cup and the Champions League, Arsène Wenger’s other changes will be interesting to see. John Ashdown
Kick-off Sunday 4pm
Odds H 4-9 A 13-2 D 15-4
Live BT Sport 1
Referee Mike Dean
Previous meetings Arsenal wins 63 Middlesbrough wins 33 Draws 33
Arsenal
Subs from Martínez, Ospina, Akpom, Chambers, Monreal, Mertesacker, Sánchez, Flamini, Rosicky, Zelalem
Doubtful Koscielny (shoulder), Sánchez (hamstring)
Injured Gnabry (match fitness, 21 Feb), Wilshere (ankle, 25 Feb), Chamberlain (groin, 28 Feb), Ramsey (hamstring, 7 Mar), Arteta (calf/ankle, Apr), Debuchy (shoulder, Apr), Diaby (calf, unknown)
Suspended None
Form WWWWLW
Discipline Y74 R5
Leading scorer Sánchez 18
Middlesbrough
Subs from Mejías, Ripley, Fredericks, Kike, Ledesma, Hines, Husband, Nsue, Carayol, Reach, Vossen, Omeruo, Morris, Wildschut, Fewster
Doubtful None
Injured Ayala (hip, 14 Mar), Williams (achilles, Apr), Damiá (knee, May)
Suspended None
Cup-tied Forshaw, Kalas
Form WWWWWW
Discipline Y64 R3
Leading scorer Leadbitter 12