Arsenal have confirmed that Sead Kolasinac and Reiss Nelson will both miss the clash against Chelsea on Tuesday night.
The pair missed the 1-1 draw against Sheffield United at the weekend, and will again be absent as Mikel Arteta's side travel to west London.
The Gunners have confirmed that Kolasinac is still recovering from the left thigh strain that kept him out of their Emirates clash with the Blades, while Nelson is out with a hamstring problem.
Both are expected to return to full training during the winter break, meaning they will also miss the clash against Burnley on 2 February.
Sokratis was also left out of the side on Saturday after suffering from illness, but Arsenal confirmed that the Greek defender will be assessed ahead of the midweek clash.
With Kieran Tierney still in rehabilitation after his shoulder problem, Bukayo Saka is again set to deputise at left-back against Chelsea.
The teenager started against Sheffield United on Saturday, and Gunners boss Mikel Arteta was full of praise for his performance.
"I think he could (have a future at left-back) because he’s willing to learn, he is applying himself big time he is someone that's has never played (that position) before but he’s really trying to do it as well as possible," Arteta said.
"You can see that he’s got many strengths to play in that position.
"Obviously he needs games, he needs experience and he needs to improve in some areas but that's very good."
Elsewhere, Arsenal could make changes in attack for the Chelsea clash, after Eddie Nketiah returned to the Arsenal squad at the weekend.
After being recalled from his loan spell at Leeds United, the striker was set to be sent out to another Championship club, but after watching him in training, Arteta opted against sending Nketiah on another short-term deal.
Speaking to reporters, Arteta admitted that the forward has a chance of featuring from the start at Stamford Bridge.
"Every player has a chance to start," Arteta stated.
"[Nketiah] is in the squad. We will assess who is in best conditions to play in who is training well and we'll make the decision based on that."
