Manchester City can regain their place at the top of the Premier League as they face Cardiff .
Pep Guardiola's men are two points behind title rivals Liverpool , but have played a game fewer.
There are also midweek Premier League fixtures for Manchester United , Tottenham and Chelsea - who are all battling for a top four place.
Meanwhile, Watford , Fulham , Wolves , Brighton and Crystal Palace are also in action.
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But first check out the predictions of chief football writer Andy Dunn as he looks into his crystal ball.
Watford 4 Fulham 0
Unlucky to be beaten at Old Trafford on Saturday and up against a team that has given up the Premier League ghost, this will be little more than a formality for Javi Gracia’s side. Expect a thumping win.
Wolves 1 Manchester United 2
United have suffered a couple of reverses on the road recently - including at Molineux in the FA Cup - but their away form under Ole Gunnar Solskjaer has, in general, been impressive.

They have momentum in the battle for a top four slot and should nick another away win.
Chelsea 2 Brighton 1
Working solely on the theory that Chelsea cannot be as poor as they have been in their last two Premier League matches - despite the fortunate win in Cardiff - Maurizio Sarri will restore Eden Hazard to the starting line-up and that should be key to getting past Brighton.
Manchester City 4 Cardiff City 1

Neil Warnock’s team were robbed against Chelsea and might be a tough nut to crack but there are no more effective nutcrackers than City. They remain in imperious form and will give their goal difference another boost.
Tottenham 3 Crystal Palace 0
The grand stadium opening calls for a grand performance and it would be no surprise if the occasion gives Spurs a serious lift.
Palace will be no pushovers but expect Harry Kane to lead Tottenham to victory in their new home.