Get all your news in one place.
100’s of premium titles.
One app.
Start reading
Daily Record
Daily Record
Health
Martin Fricker & Hannah Mackenzie Wood

Alzheimer's cure breakthrough as jab could restore patients' memories

Scientists have made a breakthrough on an Alzheimer's treatment that could reverse or even prevent the disease - for just £15 a dose.

Experiments on mice found that the jab restores memory by destroying rouge proteins in the brain, as reported by the Mirror.

According to British and German researchers, the pioneering therapy has the potential to revolutionise treatment.

It is also hoped that clinical trials on the technique, which targets soluble and highly toxic ­fragments of amyloid beta that clump into plaques, could begin in just two years.

Professor Thomas Bayer, of Gottingen University in Germany, who is co-author of the study said: “In clinical trials, none of the potential treatments have shown much success in terms of reducing Alzheimer’s symptoms.

The pioneering therapy could revolutionise treatment. (University of Cambridge/AFP)

"Some have even shown negative side effects. So we decided on a different approach.

“We identified an antibody in mice that would neutralise the truncated forms of soluble amyloid beta, but would not bind either to normal forms of the protein or to the plaques.”

The team next adapted the antibody, called TAP01, so our immune system would not recognise it as foreign.

To their surprise, the protein folded back on itself.

In tests, both the antibody and the engineered vaccine repaired the brain’s neuron function and increased glucose metabolism in the brain, bringing back the memories of the mice.

Co-author Professor Mark Carr, of Leicester University, said: “If these results were replicated in human trials, then it could be transformative.

“It opens up the possibility to not only treat Alzheimer’s but also to potentially vaccinate against the disease before the symptoms appear.”

Don't miss the latest news from around Scotland and beyond - Sign up to our daily newsletter here.

Sign up to read this article
Read news from 100’s of titles, curated specifically for you.
Already a member? Sign in here
Related Stories
Top stories on inkl right now
One subscription that gives you access to news from hundreds of sites
Already a member? Sign in here
Our Picks
Fourteen days free
Download the app
One app. One membership.
100+ trusted global sources.