Up to 20 Dublin shops will be part of the nearly 100 St Vincent De Paul outlets that will begin reopening from June 8.
The charity shops have been closed since March 16.
And the charity say this has "resulted in a considerable loss of income, which would have been recycled directly back into the community".
But almost 100 of their 234 outlets nationwide will begin to reopen next week.
“We are committed to ensuring the well-being of our customers and donors as well as staff and volunteers in the shops,” they said.
“With that in mind we have a robust and detailed action plan for each shop in relation to cleaning, sorting donations, assisting customers, signage and a range of other issues.
"All Vincent’s customers can be assured that they will be entering clean, well-organised shops, which are adhering to all the recommended social distancing and health and safety requirements.
"We will be delighted to receive much needed donations at each of our shops as they re-open after 12 weeks of closure and we would ask for your ongoing patience and understanding as we seek to receive and process these donations in compliance with social distancing requirements.
"We will quarantine all donated clothing and textiles for 72 hours before we prepare them for sale."
The full list of shops that are reopening can be viewed here.
For the latest news and breaking news visit dublinlive.ie/news.
Get all the big headlines, pictures, analysis, opinion and video on the stories that matter to you.
Follow us on Twitter @DublinLive - the official Dublin Live Twitter account - real news in real time.
We're also on Facebook/dublinlive - your must-see news, features, videos and pictures throughout the day from the capital.
