Alder Hey Children's Hospital is to limit visitor numbers from today to prevent the spread of coronavirus (COVID-19).
The West Derby hospital said it was introducing the measures in order to protect patients, staff and the public.
It means that from today, visitor numbers on the inpatient wards, outpatients and emergency department are being restricted to a maximum of two close family members or carers each day.
In line with NHS guidance, it is urging anyone who displays symptoms of coronavirus - such as a new, continuous cough or a high temperature - or tested positive for COVID-19 to avoid visiting the hospital altogether and to self-isolate.
In a statement posted on its website, the hospital said: "We want to maintain contact and support between patients and their families and carers, whilst ensuring that we take measures that prevent the spread of the infection.
"These measures reduce the possibility of the virus inadvertently being brought into the hospital and help to keep vulnerable children safe.
"We appreciate that this may be difficult but ask that you follow these rules to help our staff care for your child safely, while keeping other patients, visitors and staff safe during this period."
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The statement adds: "In unusual circumstances where no other carer is available or your child is very sick, it may be agreed that you can visit while you have symptoms.
"This will need to be agreed with senior ward staff and you will need to keep to strict rules, including isolation within your child's room, to prevent risk to other staff, patients and visitors."
