NatWest Group is to cut around 550 at Royal Bank of Scotland and NatWest branches and close one of its London offices.
The company said it had already had sufficient applications so it will not need to make any compulsory redundancies.
Around 550 full-time equivalent roles will be lost across the branches and its premier banking arm, with branch managers, premier banking managers and personal bankers among those affected.
"We have to respond to changing customer behaviour and the rising customer demand for digital banking services," the bank said in a statement.
"We have taken the decision to invite applications for voluntary redundancy and will support those colleagues who apply with a comprehensive support package.
"There will be no compulsory redundancy as a result of this announcement."
The company also said it is planning to shut down its Regents House office in London, which has enough room for around 2,500 people.
"Our ways of working had been evolving, even before the coronavirus pandemic," it said.
"We have been reviewing our London property strategy to better reflect how we will work in the future.
"As a result, we will exit Regents House, and will reconfigure our London remaining properties at 250 Bishopsgate and 440 Strand.
