The pharmacy aisle is filled with expensive, brand-name products. These items have big marketing budgets and familiar logos. However, there is a simple secret to saving a huge amount of money. The store-brand version of an over-the-counter (OTC) product is almost always right next to the brand name on the shelf. The U.S. Food and Drug Administration (FDA) requires these generic products to have the same active ingredient, in the same dosage, as their brand-name counterparts. You get the same medicine for a much lower price.

1. Tylenol vs. Acetaminophen
Tylenol is one of the most famous brand names in the world. Its active ingredient is acetaminophen. The store-brand bottle right next to it is simply labeled “Acetaminophen.” It is the same medicine. It will provide the same pain relief for a fraction of the cost.
2. Advil/Motrin vs. Ibuprofen
Advil and Motrin are the two major brand names for the anti-inflammatory drug ibuprofen. It treats pain, swelling, and fever. Your store’s private-label bottle of “Ibuprofen” contains the same active ingredient. It is just as safe and effective as the brand name. The only difference is the price.
3. Aleve vs. Naproxen Sodium
Aleve is a popular choice for long-lasting pain relief. Its active ingredient is naproxen sodium. The store-brand version is also called “Naproxen Sodium.” It offers the same 12-hour relief from pain. By choosing the store brand, you can save a significant amount of money on this common medication.
4. Bayer vs. Aspirin
Bayer is the classic and most famous brand of aspirin. Aspirin is its active ingredient. Every single pharmacy sells a much cheaper, store-brand version of “Aspirin.” Whether you are using it for pain relief or for a heart-health regimen, the generic version is a much more economical choice.
5. Claritin vs. Loratadine
The popular allergy medicine Claritin can be very expensive. Its active ingredient is loratadine. The store-brand version is often labeled “Allergy Relief (Loratadine).” It offers the same 24-hour relief. It does so at a much lower price point.
6. Zyrtec vs. Cetirizine

Zyrtec is another leading allergy medication. Its active ingredient is cetirizine. You can always find a much cheaper, store-brand alternative on the shelf right next to the Zyrtec box. It is the same medicine. It will provide the same relief from your allergy symptoms.
7. Benadryl vs. Diphenhydramine
Benadryl is a classic allergy medicine. It is also often used as a sleep aid. Its active ingredient is diphenhydramine. The store-brand version is often called “Allergy Relief (Diphenhydramine).” It is a much cheaper alternative that will provide the same effects.
8. Tums vs. Antacid Tablets
Tums is the famous brand name for a simple antacid. Its active ingredient is calcium carbonate. The large, store-brand bottle of “Antacid Tablets” contains the same active ingredient. It will provide the same relief from heartburn for a much better value.
9. Pepto-Bismol vs. Bismuth Subsalicylate
The iconic pink liquid Pepto-Bismol treats a variety of stomach ailments. Its active ingredient is bismuth subsalicylate. The store-brand version is often a similar pink color. It is the exact same medicine that will provide the same relief for a lower cost.
10. Imodium vs. Loperamide HCI
The anti-diarrhea medicine Imodium has an active ingredient called loperamide hydrochloride. The store brand is often called “Anti-Diarrheal.” It contains the same ingredient in the same dosage. It is a much more affordable option for a common health issue.
11. Neosporin vs. Triple Antibiotic Ointment
Neosporin is the famous brand name for a triple antibiotic ointment. It is a staple of any first-aid kit. The store-brand version is also called “Triple Antibiotic Ointment.” It contains the same combination of infection-fighting ingredients at a much lower price.
12. Cortizone-10 vs. Hydrocortisone Cream
The popular anti-itch cream Cortizone-10 has hydrocortisone as its active ingredient. The store-brand “Hydrocortisone Cream” located next to it on the shelf is the same medicine. It will provide the same relief from skin irritation at a significantly lower price.
The Name Game
The FDA ensures these generic products are just as safe and effective as their brand-name counterparts. The extra money you pay for the brand name is purely for marketing and the familiar logo. By learning to read the “Active Ingredients” box on the back of the package, you can make the smartest possible choice for your wallet. It is an easy way to save a lot of money without making any sacrifice in quality or safety.
Do you usually buy the brand name or the store brand for medicine? Let us know your shopping habits in the comments!
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